Can someone help me with the following:

1. Pgta/pgtd : why is it helpful? Some people don't opt to do it?what are the risks?
2. Can someone also explain the grading(aa,bb) for embryos and the anueploid/euploid bit?

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1) My clinic strongly recommends PGT for everyone, (regardless of age). I'm 32, husband is 34. We sent 9 embryos for testing, and 6 came back normal. So thankful we did it because one of our highest graded embryos (4AA) was abnormal. This would have been the one we transferred and it would have failed.

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Oh I see. Thank you

Couple things to add:
- a lot of mixed opinions on PGT. The way it’s done is they test a very small biopsy of the embryo (like 5 cells). If all are normal, it’s euploid; if all abnormal, aneuploid; if mixed, mosaic. Mosaics are now being shown to have almost as high success rates as euploids and there’s some evidence even aneuploids can self correct in the womb. That said, most REs will still recommend PGT especially if you have multiple embryos.
- grading is highly subjective and will vary quite a bit by lab and by the embryologist doing the grading. On the chart shown above, I would take that directionally. I would definitely not discard a euploid CC as that still has a decent chance of success (25-40% depending on the clinic).

I’m honestly a bit torn on PGT. I’ve always done it because I get a decent number of embryos but I had one round where I sent in 5 and only one was normal (it was a CC). Part of me wonders if maybe I should have rolled the dice on the other 4. But you’re always gonna have doubts in this journey I guess.

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*Wasted embryos. I have no idea why it typed enrollment

Fertility IQ had a lot of good literature on this

Read some here. They seem to recommend that pgt is still in research phase and healthy embryos can be lost in this process

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