When allergies and anxiety collide...does anyone here on an SSRI also use a nasal steroid like Nasonex, Nasacort, Flonase, etc. for allergies? I am suffering majorly this season but every time I use Nasonex I get a bloody nose. This has never happened in years past, the only difference is that I started Paxil last fall. Any possible connection?

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I don’t know. I remember my antidepressant actually cleared some of my allergies. Allergies are a form of inflammation and stress so antidepressant may have some second hand connection to those mechanisms. Try Nasocort or Flonase sensimist. You can also try arm and hammer saline spray


Not on ssris, but I definitely sometimes get bloody noses from nasacort. It’s a common side effect.


I would see an allergist to make sure there isn’t something else going on- I’m on Lexapro and take Flonase and haven’t had that issue. Might be worth checking out, sending you good vibes from a fellow anxious asthmatic ;)

I’ve been on SSRIs and steroid nose sprays for years (and have had three sinus surgeries), and while you should check with your doctor to ensure your particular circumstance, it’s highly unlikely there is a connection.

PWC and Associate 1 above hit the nail on the head - steroid nose sprays often cause bloody noses, especially seasonally and dependent upon your home environment’s humidity. Your doctor is likely to recommend a saline nose spray or saline rinse (both available at most drug stores), or depending on how frequently you’re using the nasal spray and for what reasons, may switch you to a different brand or type of spray (brand, OTC, prescription, primary ingredient).

I’m on sertraline and an azelastine spray. I’ve always had a nose that bloodies easily, and if anything, the spray seems to stave that off a bit.

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