If a start-up is doing fairly but not exceptionally well, would investors usually back out after the seeding round?

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If the seed investors are capable of investing more, if the company is headed in the right direction and the startup is making efforts to address shifts in plan or slower than expected market conditions, then yes.
Investors know that forecasts are lies, so missing business plan targets alone is not a reason to come up with another round.

If the seed investor has limited resources or only wants to do early stage deals, then you’ll need to find the money elsewhere. Also if there was a fundamental market or regulatory shift, that could impact also. Good luck!

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