What are the most impressive innovations 💡 that you have seen in Life Sciences recently?

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Vaccine development in <1year

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It was a proof of concept for mRNA vaccines, so probably yes. On another note Oxford just published results for a good Malaria vaccine.

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A few that analysts are keen on:
-mRNA vaccines (duh)
-The KRAS inhibitor data from Amgen seems like a pretty strong bet for “next wave” of meaningful oncology innovations
-Lp(a) as a target in cardiovascular (Novartis)
-Humira biosimilars coming to the US in 2023 will be pretty fascinating to watch how the market responds
-Off the shelf CAR T hopefully coming in the next 5 yrs
-CVS, Amazon, etc moving into the provider space (not just pharmacy)

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Strong list

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Is this research for your next Megatrends?

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Haha....nah. Just for my curiosity. Would love to hear from folks in the field directly

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The sheer number of vaccines that were developed so rapidly is definitely a big one and the mRNA technology.

Healthcare delivery is also seeing some significant change that is accelerated by Covid.
-more integrated devices and data from wearables and the platforms are being set for more implantable devices
-partnerships between pharmacies and platforms like CVS and Doordash could have a massive ripple effect
-multi-dose packaging and other methods to drive adherence
-improved pricing transparency on drugs
-point of care changes be it the expansion of Minute Clinics and WalMart Health clinics as well as on demand care via platforms like Amazon Care
-telehealth and telemedicine

Ultimately life sciences and healthcare will see more convergence and new models will start to emerge. The entry of big tech will ramp things up on the physical side as well as technology.

Allogeneic CART
Gene therapy for deadly diseases eg SMA

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