I’ve been taking Letrozole 2.5 mg, 3 tablets a day (7.5 mg total) from Day 5 to Day 10 of my cycle. On Day 13 ,My follicle measured 16 mm, but my estradiol level was only 54 pg/mL, which seems low for that follicle size.

Has anyone else experienced low estrogen despite taking letrozole. Thank you in advance for sharing your experience/thoughts.

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Doesn’t letrozole decrease estrogen levels?

I do not know. My nurse practitioner says it is on lower side but not disqualifying. Chat gpt said the same as well.

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