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I've been to both and I'd say go to Colombia. Panama City is a lot of fun and has great night life but Panama is a metropolis with all walks of life so I didn't get a great sense of Panamanian culture when I went. Colombia on the other hand has awesome nightlife as well as an amazing culture that was very welcoming. We did a quick 5 day trip, flew from DC to Cartagena and spent Wednesday-Friday in Cartagena and then hoped on a 45 minute flight to Medellin and stayed there till Tuesday and then spent two days on the beach in Cartagena. If you go to Medellin make sure to get out of the El Pablado area at least once, it's a nice place to stay because it's safe but it's also very upscale and boogie so to truly get into the Paisa culture you need to go and hang in some other barrios.
Why would anyone consider going to Panama when you can go to Colombia
Have been to both, go to Colombia hands down
Paisas 😍😍😍
Been to both. Explore Colombia since you have a week. Panama is a weekend trip.