I have 1.5 YOE in biotech industry after my PhD. I'm currently getting 150k (high cost of living city) and 1) should I get paid higher? 2) I'm planning to leave if I'm not promoted to senior by end of year, should I wait longer? Or negotiate for higher salary increase?

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You're better bet is to stay put negotiate.
You're making much more than most people at this time.
Banking your money live within your means

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$150k for someone in HCOL and with a PhD sounds low to me. I know data scientists with bachelors and 3-4 YOE making that much or more. If not a promotion, definitely negotiate for a higher salary. At the same time though, definitely make sure this is something you bring up with back up info (I have worked on xyz, completed xyz project, etc) to your manager. Unless they’ve specifically given you a timeline for promotions/raises I wouldn’t just go in expecting one by a certain time. Good luck!!!

I would search jobs in your area with the same title and see how much the going rates are

My company is a smaller biotech, so I'm not sure if I can compare with the bigger (i.e. abbvie, biogen, etc)

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