What chance do I, a PhD scientist working at a national science lab, have of moving into the quantitative finance space in the current job market? I didn't go to a top-tier school, but I think I'm pretty decent at what I do. Also, I know that I could learn whatever skills I'm lacking while on the job, but would potential employers have an appetite for an ex-scientist, who would need to learn a few skills on the job, in the current climate?

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Prep yourself by learning the theoretical underpinnings first,. No doubt you can do the math. What about quant finance appeals to you? What insights does a valuation model for some financial instrument give you? How can you apply those insights? Ultimately QF is about valuation. Couple this with solid tech (Python is good) and you're better positioned to have a cogent discussion with a hiring manager.

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pretty good really

Depends on the firm. I think you have a shot at a lower tier one, since your degree isn’t “top tier”. Just make sure your python is really really good

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