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What kind of role in medical affairs are you applying to?
Not sure what your background is but ideally you'll need prior medical affairs experience, or be able to show that you have relationships with existing KOLs within the therapeutic area you are applying to. Even better if you are a kol already. This kind of role is driving the medical strategy and you have to be qualified enough for the thought leaders to take you seriously. Presumably you have a MD or maybe a pharmD?