Been on my same med dosage for a year now and finding that it wears off quicker now so my focus declines in the afternoon while still working.

I’m surprised by this because I’m about 25lbs lighter than when I started so I figured it would metabolize differently and the dosage would remain as effective.

Time to up my dosage? When did you notice you needed to increase? I’m on Vyvanse btw 40mg.

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They may have to adjust your dosage. I experienced the same and now I get 2 doses a day, 20 MG in the AM and 10 MG in the afternoon. This helps keep my concentration at pace. DYI I’m on Ritalin but talk to your provider and ask if splitting the doses is effective.

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To avoid this exact situation, I rarely take my meds on the weekends. Of course there are times when I really need it on a Saturday or Sunday but most of the time I prefer not feeling the effects over the weekend. I find that this has helped me a lot when I take it again on Monday.

Also agree with Deloitte 1. In addition to 30 mg Vyvanse, I have a subscription for 10 mg IR adderall. I tend to take that when I hit a wall at 2-3 PM or have a light work day where I don’t need a full vyvanse.

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I drink lots of coffee on the weekends and don’t drink any during the week

It's definitely possible to build up tolerance to stimulant drugs. Weight probably does affect the effects but I think it's being outweighed (no pun intended) by your increasing tolerance.

I'd recommend either skipping one or two days a week (to reduce your tolerance), or talking to your psych/doc about either a IR booster or an increased XR dose.

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