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66% effective at preventing infection
But 85% effective at preventing severe symptoms, and 100% effective against hospitalizations and death (in the trial sample size)
Single dose, no complicated cold chain logistics. This is a huge weapon against the virus, and could be used for young/low risk folks, while mRNA vaccines are used for higher risk groups (just hypothesizing here; I’m no epidemiologist)
I think this vaccine would still drastically reduce transmissibility — both lower viral load and lower length of disease
Also, I think it will be more difficult to get younger patients to get two doses at a reduced number of locations, whereas higher risk patients should be more motivated to do so
Yes. We hit two home runs with Pfizer and Moderna. But we can score runs with Doubles and Triples too
Rising Star
It's about on par for just part 1 of any of the 2 part vaccines
Rising Star
I think I read somewhere the annual flu shot is about this effective.
Rising Star
Yes, but flu is less deadly than COVID (at least at this point). Also, I wonder how this is strong when peer products are citing higher probabilities of safety.
This is on par with most vaccines historical performance
Rising Star
Don't forget the difference between effectiveness and efficacy either. The effectiveness JnJ is reporting is likely more realistic as COVID cases cases were significantly higher as a whole during evaluation compared to Pfizer/Moderna's Phase I-III studies, and the lockdown measures became less stringent/less followed, meaning the effectiveness Pfizer and Moderna reported were likely inflated
Rising Star
It will need boosters, big deal
J&J built an old school proven by billlions of doses vaccine. It’s a dead cold molecule and they manipulated the protein receptors, it’s basically a flu shot and you get one a year at cvs, that’s how you get the whole planet.
Is mRNA better, yes, but until enough exists J&J like AZ which is similar save they used a gorilla cold virus molecule, are the key to masses and key to the 3rd world,
French figured it out Sanofi is now manufacturing Pfizer vaccine, why isn’t Merck?
Rising Star
It’s one dose and need boosters, get it approved