Anyone dealt with early second trimester miscarriage with PGT normal embryos after FET? We transferred two AA normal embryos-- one was a blighted ovum and just lost the other early in second tri. If you have, what did you do differently the next time around for more success? Getting old and just crushed at losing both our normal embryos and 6-9 months.

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First, I am so sorry you are going through this. I very recently had 2nd trimester loss and am getting through that devastation. As context, I already have two babies who were conceived from IVF. My recent, third pregnancy was spontaneous and the subsequent loss was due to a chromosome issue that only became apparent in week 14. I share this as context to questions below.

Reading your post made me consider some questions that I would ask of your RE and/ or OB to understand what happened. I truly hope these questions are not saying the wrong thing.

First I would be asking my RE, regarding the first embryo, is how an AA embryo resulted in a blighted ovum. That doesn’t make sense to me. But I’m not a scientist so perhaps there is a simple explanation.

For your second embryo, do they have a hypothesis on why you miscarried? Did they do NIPT bloods or NT scan? Did they offer testing of the fetus or microarray?

Separately, this is devastating. You’re not alone. I have had many moms friends and friends of friends reach out, who - in more cases than I would have expected - experienced late stage losses with PGS tested embryos.

And every loss is devastating. The length of pregnancy is not an barometer of the grief we feel.

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Thyroid issues?! So sorry for your loss.

I’m so sorry, OP. I lost my first pregnancy - a normal AA embryo - at 14 weeks, and never got an answer (they messed up the placental / tissue tests, though we know it wasn’t chromosomal). I then switched clinics and the doctor noticed an arcuate uterus that may have contributed. If you already had two healthy pregnancies than maybe this isn’t relevant to you, but since it was my first and we couldn’t find anything else, I’m leaning on that. Unfortunately I just found out our second transfer, also AA normal embryo, was a blighted ovum, so I’m hurting like you are and just confused. I’m glad we’re not alone, at the very least.

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