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I’ve got arthritis too. I first got diagnosed with osteoarthritis at 28. Ugh. It sucks. I took HRT for a few years, but around the first of the year I stopped taking it because I’m on another medication that stops the hot flashes for the most part. An increase in arthritis pain was probably the first thing I noticed as a side effect of stopping HRT. I also spent a month or so with mood swings, but I think that has calmed down. Maybe my husband would disagree... Anyway I’ve embraced jar openers, and I take Tylenol or ibuprofen on the worst days.