Without fail everyday around 4pm I encounter low-grade depression. This has been ongoing for years and I've tried to combat it through making plans, exercising etc... Anyone else experience this and found healthy solutions?

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Sugar or caffeine crash? Mental exhaustion? Dehydration? Poor nutrition? Lack of sleep?

Recommend going to a registered dietician and getting consistent exercise 4 times a week.

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The reliable timing of 4 pm suggests a pattern. Does this happen every day, or every WORK day?

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Definitely has to do with your blood sugar level/caffeine crash. Have felt this way for years as well. What helps is taking a quick walk for fresh air around 3PM and I’ve noticed it doesn’t affect me as much.

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Same! 4PM is more or less dreading time in a workday and body gets sluggish. I and my work besties used to perpetually take a snack or coffee break at 4pm for 20/30mins… it may happen to step down for a walk or just go to local cafeteria. Bt step away from monitor at 4pm.
OP if you are working from home, apply the same technique. Get 30mins of steps on your steps tracker but take 30mins of break and coffee/green tea at 4pm every day!

First plan of action that I can think of, that has been suggested to me by my psychiatrist and therapist, is to really take a look at how you go about the day.

Are you working without taking any rest periods? Is worked constantly being piled onto you, rerouted to you, etc.? Is there something that regularly occurs that affects you mentally, emotionally, and/or physically?

I’ve personally had to hyper analyze my days because I’m prone to internalizing stress, to the point where I don’t even realize I’ve had prolonged stress until it negatively affects my health (e.g., acid reflux, weight gain, cravings).

Once you’ve narrowed down at least one (or a few) things that may contribute to that timed depression, you can start working on a game plan to minimize/alleviate that thing.

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Same, therapy lol

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